My first retrieval was an antagonist protocol, and we only got one poor quality embryo (3CB). Seven cycles were cancelled with no response - some after more than 2 weeks of stim. The lupron over suppresses my ovaries and they don't respond well even to high doses of Bravelle or Follistim or Gonal-f, so I am trying the antagonist protocol next with ganirelix. But I'll let you know if I respond better! I'm 36 & TTC 2 yrs. Short protocol for low responders We have discussed GnRH agonists as a suitable treatment for low responders. My first stim cycle was Antagonist and we actually did cancel ER. Both hCG and Lupron effectively trigger maturation, (necessary for IVF success), but Lupron is better tolerated. While some practices make a big deal over the choice of gonadotropin (some use only recombinant FSH, such as Gonal F or Follistim while others primarily use urinary hMG drugs such as Bravelle or Menopur), most studies suggest that there is very little if any difference in pregnancy rates between the different medications. NT- all looks good. The clinic I was with was horribly unorganized, I never saw my doctor, and dealing with insurance was a nightmare which made every, Looking for advice Adding Cetrotide. I'm trying to dig up information about stim doses (since Dr C says I'll still be on a lot of meds?) My first retrieval resulted in no viable embryos. Our beautiful little girl arrived January 2015! Please!!!!!!!!!!!!! Just curious-What was your medicine protocol. So I don't have anything to add but I'll be watching you;-). IVF3 (ICSI/CCS): Antagonist with EPP My little one is a success story from MDL! I am 28. I am doing estrogen priming in advance of my next IVF cycle, so I am also due to start estrogen priming 10 days before my period. HOORAY. As the poor responder is one of the more challenging issues facing the reproductive endocrinologist today, and as there are no magic bullet regimens to stimulate these patients effectively, many alternative protocols to the flare have been proposed. Anyone have anything reassuring to say about it? So, we concluded that the microdose flare-up protocol may have a better outcome in poor-responder patients. Then you start microdose lupron on CD2 for a few days and then you add your stimulation medication. Any success stories for low responders of Estrogen Priming cycle? Bzeety & Hootie- you guys give me sooo much hope, seeing that you both had success with this protocol after being through the ringer so many times. What was your protocol before? Long Lupron protocol. I'm starting IVF#3 on November 14th. With IVF#2, we did MDL. The Finding a Resolution for Infertility Support Community connects patients, families, friends and caregivers for support and inspiration. Oh yeah, forgot to say that I took Lupron for 2 days then added Menopur and Follistim and I stimmed for 7 or 8 days. This treatment protocol is known as a "microdose flare." The initial injections of Lupron stimulate the pituitary gland to secrete its own natural FSH and LH (aka a flare), in addition to the FSH and LH you get from the other two injectable fertility medications. I will access my frozen eggs in.june hopefully. 505 The short protocol also known as microdose or flare protocol takes advantage of the body's initial response to Lupron with a surge of hormones for several days that stimulates the ovaries. However other had mature egg and we did Icsi by it didn't grow from there. Instead we are doing estrogen priming followed by microdose lupron. With my day 6 u/s, the lupron was reduced to 5 units in the morning a, Hey, if you've done the EPP protocol, can you tell me more about it? Create an account or log in to participate. I am a little concerned that I am supposed to take 300 iu's of Gonal-F. Honestly, I felt like he was guessing, but I suppose that's what it's all about sometimes! Thanks! I just started a new one with estrogen priming, microdose, letrozole and only gonal f. No menopur. IVF round 1 was a miserable failure with an almost cancelled retrieval and no embryos to freeze or transfer. 6R. Estrace(90 tabs)-estrogen I did 2 FETs but did not get pregnant, Now I have just one embryo left. As access age, Tarlatzis BC. 5 retrieved, 3 fertilized, 2 transferred on day 3, none froze, BFN. Had 19 follicles on my baseline, which was really good for me, but I ended up with 4 large follicles . I had blocked tubes and everything else with me and DH was normal. I miscarried the normal. I go in for a check Thursday am. I'm doing it now the patch seems to be less obnoxious than the pill, but I'd like to hear about peoples experiences. numbness or tingling of the hands or feet. Apparently we waited too long ? After two failed IUI cycles, my RE decided to start me on an EPP to prep for next cycle. This is a community for those who have gotten pregnant after a struggle with infertility. I dont want to keep trying protocols and not succeeding. Did one cycle of IVf with 450 of gonal F and then cetrotide and ovidrel. [curious1] lcurtis8, it's a hormone that we produce plentiful as younger adults; as we age it decreases. The educational health content on What To Expect is reviewed by our medical review board and team of experts to be up-to-date and in line with the latest evidence-based medical information and accepted health guidelines, including the medically reviewed What to Expect books by Heidi Murkoff. 0 The most commonly prescribed stimulation protocol in the United States uses BCPs, leuprolide acetate (Lupron) to prevent ovulation, gonadotropins such as follicle stimulating hormone (FSH) or human menopausal gonadotropin (hMG) to cause the eggs to develop, human chorionic gonadotropin (hCG) to cause the eggs to mature, and progesterone to We have a new nurse who's not a dumb bitch (like my other nurse that failed to tell me I would have a withdrawal bleed after stopping BCP before IVF). This typically takes 8-12 days, during which time the stimulation is monitored using a combination of vaginal ultrasound and a blood estrogen level approximately every 2-3 days. sometimes a bcp is used for this same purpose. What to Expect supports Group Black and its mission to increase greater diversity in media voices and media ownership. Have done 3 IUI's - 2 w. clomid and 1 with Gonal - F. I had a hyrdo on my left tube which had been removed and no left ovary to be found :( But I do have a good right tube & ovary. Any success stories ? It is very reassuring to know that many of you have had great success with this protocol, and it is awesome to see that several of you are currently pregnant after doing this protocol!! The educational health content on What To Expect is reviewed by our medical review board and team of experts to be up-to-date and in line with the latest evidence-based medical information and accepted health guidelines, including the medically reviewed What to Expect books by Heidi Murkoff. Microdose lupron/micro flare lupron vs agonist-antagonist ivf protocol. xb```"V2>c`0p40. Hello, What should we try that we haven't already? He takes my input and works with me. How do they decide? It seems to be less common, since most clinics batch cycle, and this one is based off your individual cycle. Hi! Well, my 4 long months of waiting to cycle again are finally over, and I am starting IVF #4 on Friday. . February 2011 Anyone have good success? Please specify a reason for deleting this reply from the community. I don't fit into either of those categories, but I am excited to try a different protocol. Did acupuncture, Chinese herbs, modified diet, re-tested and FSH was 7 / Estradiol 47/ AMH .4 Got 9 eggs, 4 were mature, 3 fertilized, 2 didn't make it and the 1 that made it to blast tested abnormal. <<7e73b458605e884a9eec5f5e9aeedda8>]>> Earnest Letter. Infertility doesn't go away after the first positive test. For how long was the MDL given ? 1Frostie. This is my second attempt at ivf my first ivf was unsuccessful no embryos made it to day 5. This educational content is not medical or diagnostic advice. Was wonderin, Hi ladies - Don't be offended with this NOOB question! Pressing Forward Use of this site is subject to our terms of use and privacy policy. So I had been on estrogen patches/PIO after failed transfer from my frozen eggs and then continued to delay my period. Team Purple. They said I would, I just completed a second round of IVF/ICSI. I replied to your original post, just wanted to say I'm glad you also posted over here to get more stories. IVF#4 (Dec2013/Jan 2014): Microdose flare+Saizen+testosterone 4 eggs retrieved, all mature and fertilized by ICSI, ET of 1 6-cell embryo an 1 8-cell embryo graded 2 and 3. Also planning to incorporate HGH and low dose aspirin this go round. However, I think I am in the minority as clearly it works incredibly well for some. Anyone done this protocol? Microdose Lupron Flare Protocol. That cycle we got 9 retrieved, 7 fertilized and 5 good quality blasts and a successful FET a couple of months later. Thank you. 1) focus on the quality (not quantity) of eggs. Start by selecting which of these best describes you! Er2: 7 mature eggs, follistim 250 iu with ganirelix, no priming. A couple of things to keep in mind with MDL, I started with a AFC of 7 (pretty average for me) and for the first several days of stimming (5 at least) there were only 7-8 growing and my E2 was super low. With IVF#2, I got 16 eggs, 15 of which were mature. We started our IVF journey in 2014. We use during the pill from person through luteal phase. She has already been prescribing me an aggressive protocol (microdose Lu, So a little bit about me. This medicine reduces the amount of testosterone in men or estrogen in women. 0000002680 00000 n The retrieval resulted in 8 eggs with the microdose lupron protocol. sudden, severe decrease in blood pressure and collapse. No frosties. How to Cope After a Failed IVF Cycle Cry and Sob and Wail. I'm looking for any feedback on microflare protocol using microdose lupron and ICSI. 0000002919 00000 n Start Lupron: Start your microdose Lupron 20 units subcutaneous injection twice a day. Hence we see mini-IVF protocols used at places like New Hope Fertility in NYC (http://www.newhopefertility.com/?topic=minimal-stimulation-mini-ivf) and the Infertility Center of St Louis (http://www.infertile.com/closlook/biograph.htm); and, 5/15 fainting. Good luck on thursday. During the first few days of Lupron, the ovaries are stimulated by the natural pituitary hormones (the flare . '13 - We will try again with EPP. Lupron Trigger During Stimulated IVF Cycles. think twice before sharing personal details, foster a friendly and supportive environment, remove fake accounts, spam and misinformation, delete posts that violate our community guidelines, reviewed by our medical review board and team of experts. None froze, BFN wonderin, Hi ladies - do n't fit into either those. The ovaries are stimulated by the natural pituitary hormones ( the flare Now I have just embryo! Of gonal F and then you start microdose Lupron protocol selecting which of these best describes you to be common! Which of these best describes you tubes and everything else with me and was! Infertility Support community connects patients, families, friends and caregivers for Support and inspiration was a miserable with! 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