2023 American Animal Hospital Association. It is a safe extract, which can be taken long term. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. The Journal of General Virology. I give one 300-milligram capsule once an hour for eight doses, emptied out and mixed with water and given with an eyedropper. International Journal of Antimicrobial Agents. Kabara JJ. Some people take monolaurin as an immune booster. However, experts are unsure how the body converts lauric acid into monolaurin, and at what rates. Commonly used in dogs; injection pens (in either 0.5 U or 1 U increments) available for dogs and cats. Looking to try monolaurin? A study in two dermatology clinics showed that coconut oil, which contains monolaurin, might help people with Staphylococcus aureus infected eczema. Unfortunately, it is difficult to estimate just how much of the lauric acid from coconut oil is converted to monolaurin, but one article suggests that it is less than 6%. Powder: Monolaurin by nature has a strong soapy and bitter taste. Monolaurin has shown antibacterial and antiviral effects when examined in test tubes and culture dishes, which is referred to as in vitro testing. An Antibacterial Skin Spray that contains the same monolaurin as well as American Society for Microbiology 9 February 1998. "The most effective antimicrobial compounds against all morphological forms of the two tested Borrelia sp. Monolaurin is a fat found in coconut oil and breast milk. It's then bound to a glycerin using a proprietary molecular distillation process. One (1) blue scoop = 1 tsp =3,000 mgMonolaurin. A review of monolaurin and lauric acid. (2007). WebThe study found that seven of these natural product extracts at 0.25%-0.5% had better activity against the stationary phase B. burgdorferi culture than the control antibiotics doxycycline and cefuroxime, both of which are commonly used to treat Lyme disease. Some people report short-term side effects and caused by the alleged die-off effect. Here are 9 teas that help treat stomach problems. You can take monolaurin on an empty stomach, however those with sensitive stomachs should take monolaurin with food as the supplement has a natural "soapy" taste which may be unpleasant to some. However, monolaurin (5% glycerol monolaurate in warming jelly or saltwater) greatly increased genital herpes transmission in mice [43]. Monolaurin is a chemical derived from lauric acid, a component of both coconut fat and breast milk. Lauric acid levels in breast milk can vary. Monolaurin tastes quite bitter so most people prefer to take their daily amount with other capsules or tabs and wash them down with any liquid. A recent study found that monolaurin has potential as an antifungal treatment for candida albicans one that can also reduce a pro-inflammatory response. Important Information:To help avoid a Herxheimer Reaction, consider gradually building up to a full amount over the course of 7 to 10 days. September 2006, Volume 41, Issue 9, pp 851858, C A Francois S L Connor R C Wander W E Connor. Theres no clinical evidence whatsoever to support the use of monolaurin. Our team thoroughly researches and evaluates the recommendations we make on our site. Lauric acid converts to monolaurin in the body [4, 5]. Label (Claims, Formatting, and Research): Always look for proper citations, label formatting, and research when selecting a monolaurin brand, as this demonstrates FDA compliance and a well-managed operation. Both monolaurin and coconut oil, which contains lauric acid, are possibly best known for their antifungal effects. Coconut oil is an edible oil harvested from the meat of mature coconuts (Cocos nucifera). Best taken regularly over time for results. It can be life-threatening in immunocompromised people. Also known as glycerol monolaurate or glyceryl laurate, monolaurin is used in cosmetics and as a food additive. [Ref # 27], Delivery: Levels of lauric acid and other acids including myristic, alpha-linolenic, arachidonic, and eicosapentaenoic acid were significantly lower in women who had caesarean deliveries versus vaginal deliveries [Ref # 22]. WebInstill 1 drop into the affected eye (s) every 6 to 8 hours as needed. Mohammad MA, Sunehag AL, Haymond MW. May people ask, why dont I just take coconut oil?. However, users complained about its bad taste. Kabara JJ, Vrable R. Antimicrobial lipids: natural and synthetic fatty acids and monoglycerides. Monolaurin supplements have not been approved by the FDA for medical use. Some people claim that monolaurin can trigger a die-off reaction by killing microbes in the body, but theres no scientific evidence to back them up. Monolaurin attacks the lipid membrane of the Herpes simplex and Herpes zoster Viruses Researchers are currently investigating its usefulness in clinical settings. We were the first to emulsify monolaurin to create high quality topical blends with the addition of powerful nutrients such ascolloidal silver,phospholipids,plantessential oilsand more. The recommended dose is one drop of . 1998 Jan; 180(1):182-5. Monolaurin had no adverse effect on gut bacteria in dishes. For example, an 80 lb. The improvement in energy is the most talked-about. 2000 May; 182(9):2668-71, Carpo BG, Verallo-Rowell VM, Kabara J. All readers/viewers of this content are advised to consult their doctors or qualified health professionals regarding specific health questions. Equivalence of lauric acid and glycerol monolaurate as inhibitors of signal transduction in Staphylococcus aureus. Dermatitis: November-December 2008 - Volume 19 - Issue 6 - p 308315. However, there is insufficient data to back up the claim that people get only 4% of monolaurin from all types of coconut oil. Dosing Overview Monolaurin is a chemical made from lauric acid, which is found in coconut milk and breast milk. But for now, theres little downside to taking a monolaurin supplement. In theory, they may be beneficial to people with memory impairment, but evidence is lacking [51]. Alphagan P Dosage. Ana received her MS in Pharmacy from the University of Belgrade. Monolaurin was researched against the parasite Giardia lamblia [38]. Have in mind that this is only a theory based on cellular studies [15, 16]. Use Alphagan (Ophthalmic) exactly as directed on the label, or as prescribed by your doctor. The opinions expressed in this section are solely those of the users who may or may not have medical or scientific training. Frustrated by the lack of good information and tools, Joe decided to embark on a learning journey to decode his DNA and track his biomarkers in search of better health. WebThirty-two mixed-breed male and female cats were blocked by sex, arranged by body weight from greatest to least, and allocated to 4 groups of 8 (4 male, 4 female) cats, Capsule Count per Bottle (60, 90, 100 capsules): Since monolaurin can be taken over long periods of time, and doses may increase during an immune challenge, having some extra capsules on hand can be advantageous. Joe Cohen flipped the script on conventional and alternative medicine and it worked. ALPHAGAN P (brimonidine tartrate) ophthalmic solution may be used concomitantly with other topical ophthalmic drug products to lower intraocular pressure. Roughly 40 to 60% of coconut oil is comprised of lauric acid [38]. Read more research on Monolaurin and Bacteria. In theory, the antimicrobial effects of monolaurin could act as a boost to the immune system. Monolaurin should be avoided during pregnancy and breastfeeding due to a lack of safety data. Its effect on gut bacteria in humans is unknown [11]. Monolaurin has a long history of clinical research which explore its potential to support a healthy immune response. These include several species of ringworm. A generally accepted dosage range is 1 -3 capsules 2 - 3 times daily (1800mg to 5400mg), but some customers prefer lower or Immune Support - A proprietary blend of cat's claw, monolaurin, and 1000 IU vitamin D3 to support a healthy immune system.*. Studies have investigated the antimicrobial effects of coconut oil, lauric acid, and monolaurin, but most of these studies have been conducted in test tubes and petri dishes (in vitro). It is likely that the appropriate dose of monolaurin depends on several factors, including: age health status presence of other conditions If someone is taking coconut oil Bergsson G, Arnfinnsson H, Karlsson SM, Steingrmsson O, Thormar H. In Vitro Inactivation of Chlamydia trachomatis by Fatty Acids and Monoglycerides. promoting collagen growth. Learn what studies have to say about its ability to combat conditions from acne to. WebGlargine (Lantus), q 12 hr based on the estimated ideal body weight of the cat and BG levels: This equates to 1 U q 12 hr in the average cat. We avoid using tertiary references. Its important to note that Kabara has a vested interest in selling his supplements, so his information may not be reliable. It is recommended to start with low doses of monolaurin and slowly build up to a higher dose over time. If more than one topical ophthalmic product is to be used, the WebMonolaurin is used for the common cold, flu (influenza), shingles ( herpes zoster ), and other infections, but there is no good scientific evidence to support its use. Clinical research and guidance do not include children, and therefore the safety and efficacy are unknown. Pellets are relatively expensive per-jar and potentially inconvenient to transport / fit in pill organizers. The main risk associated with consuming or applying monolaurin relates to those with a coconut allergy. Peak Action (Nadir) and Duration of Effect, Cats0.250.5 U/kg q 12 hr (not to exceed 3 U per cat).5. There are no known risks, interactions, or complications with monolaurin as a dietary supplement. Monolaurin is found naturally in coconut and palm oil, which has been used in personal and commercial food preparation and production. Monolaurin can be taken daily as a dietary supplement. Carpo BG, Verallo-Rowell VM, Kabara J. Journal of Bacteriology. "Here, we describe how dietary medium chain triglycerides (MCT), previously found to promote lipid catabolism, energy expenditure and weight loss, can ameliorate metabolic health via their capacity to improve both intestinal ecosystem and permeability. Your email address will not be published. Its also being studied against the viruses potentially responsible for infections in chronic fatigue and immune dysfunction syndrome [47, 48, 11]. According to one hypothesis, monolaurin may stop viruses from multiplying by sneaking into the fatty layer of their cellular membrane. Researchers hope that one day monolaurin could be used to create a new antibiotic or antiviral medication thats effective against a broad spectrum of microbes. In addition to this, taking monolaurin was suggested to have some limited anti-obesity properties. Another study in the Journal of Drugs in Dermatology suggested that monolaurin extracts may be potent against several bacterial species that can cause skin infections, including Staphylococcus aureus and Streptococcus spp, when studied in lab settings. NOTE:In dogs, the manufacturer recommends a starting dose of 0.5 U/kg q 24 hr. WebWe find monolaurin pellets are much more concentrated and far less money per serving. Not FDA evaluated. Alphagan Eye Drops is used in the treatment of ocular hypertension and glaucoma. Comment * document.getElementById("comment").setAttribute( "id", "a43cb5a8775e488cfee57a8fb2f8c27b" );document.getElementById("a6cbe26769").setAttribute( "id", "comment" ); Save my name, email, and website in this browser for the next time I comment. Coconut oil contains around 40 to 50% of the medium chain fatty acid lauric acid, which when found on food labels is typically represented as C12. The Task Force recognizes that clients are often cost-constrained. 15,000 U/kg or 810 mg/kg, PO, q 68 h. Dicloxacillin sodium monohydrate. Available for Android and iOS devices. Many bacteria and viruses can develop resistance to antibiotic or antiviral drugs over time. St. Martin's Griffin, 2017. A 2013 study published in the Journal of Medicinal Food confirmed the results of other in vitro studies that showed the antibacterial power of monolaurin. Geriatric Then their health would begin to suffer - while those on native diets stayed healthy! One doctor and author, Dr. Richard Horowitz, whose clinic has treated over 12,000 patients over the past 26 years wrote about Monolaurin in his 2017 book: "Monolaurin, a coconut oil extract, has also recently been shown to have the ability to significantly affect three morphological forms of Borrelia burgdoferi and Borrelia garinii: spirochetes, latent round body forms, and borrelia biofilms, while simultaneously deceasing yeast overgrowth in the GI tract." Additionally, given that you've probably had it awhile, it might be prudent to look for EBV triggered antibodies which may be causing symptoms. Despite this, evidence suggests that the compound may have the following qualities: Monolaurin shows antibacterial effects against a range of bacteria including antibiotic-resistant bacteria called Staphylococcus aureus (Staph). Monolaurin is lauric acid but in a safe form for human ingestion and performs the exact same anti-microbial function. Abbreviations: BG, blood glucose; NPH, Neutral Protamine Hagedorn; PZI, protamine zinc insulin; U, units. Leaky gut is associated with chronic fatigue syndrome, asthma, autism, lupus, multiple sclerosis, scleroderma, migraines and even food allergies [Ref #34]. As a result, there are no dosage guidelines available, and the limited amount of research does not allow scientists to formulate an appropriate range of doses. MAXIMUM DOSAGE Adults 3 drops/day/affected eye 0.1%, 0.15%, or 0.2% ophthalmic solution; 4 drops/day/affected eye 0.025% ophthalmic solution; 1 application/day topically brimonidine gel. The final output is a glyceride in the form of a soapy white powder called glycerol monolaurate (monolaurin). Everything should be in moderation. It combines lauric acid from coconut oil with a plant-based glycerol (non-soy), creating the purified ester known as monolaurin [38]. Our bodyadds glycerol to other coconut acids, as well, and converts them into the monoglyceridesMonoCaprinandMonoMyristin. From there, he suggests they work their way up to 3000 mg, two to three times per day. The American Journal of Clinical Nutrition, Volume 67, Issue 2, 1 February 1998, Pages 301308, https://doi.org/10.1093/ajcn/67.2.301, Margrit Hamosh, Jerry A. Peterson, Theresa R. Henderson, Ciaran D.Scallan, Radwin Kiwan, Roberto L.Ceriani, Martine Armand, Nifin R. Mehta, Paul Hamosh. Lieberman, S., Enig, M. G., & Preuss, H. G. (2006, December 11). You must consult your doctor before acting on any content on this website, especially if you are pregnant, nursing, taking medication, or have a medical condition. Comments. Dr K put me on 2 460mg pills twice daily of Valcyte and I began to feel better within 30 days. Anyone with a coconut allergy shouldnt ingest coconut oil, but adverse effects are otherwise unlikely. All rights reserved. Without this barrier, the body may be at an elevated risk of infection. Medium-chain fatty acids, such as lauric acid, are present in coconut oil and convert into monolaurin in the body. Researchers are unsure of conversion rates of lauric acid obtained though foods like coconut oil or coconut meat to monolaurin in the body [Ref #9]. Monolaurin and the Herxheimer (Die off) Reaction. AAHA Amplify: A Group Accreditation Program, Why pet owners should seek AAHA-accredited practices, Infection Control, Prevention, and Biosecurity, FREE WEBINAR: AAHA Senior Care Guidelines, Distance Education Veterinary Technology Program (DEVTP), AAHA Guidelines Certificate Course in Nutrition, Why De-escalation Training Is Essential for CSRs, Shining a Spotlight on Ideas that Work: Veterinary Visionaries and Beyond, Practices Celebrating Accreditation Anniversaries, AAHA Board of Directors notice of position vacancies, Notice of AAHA Board of Directors slate of nominations, Tips and Tricks for Anesthetizing Diabetic Dogs and Cats, New: Top Tips for Techs and Pet Owner Resource. Many holistic doctors report that they see improvement in clients overall sense of well-being. Do not use in larger or smaller amounts or for longer than recommended. Monolaurin is a chemical derived from lauric acid and glycerin, and is a byproduct of coconut fat While the research into the effects of monolaurin in people is limited, it may be useful for the following: Monolaurin also has uses in food production and manufacturing. Research shows that monolaurin is an effective killer of bacteria, including antibiotic-resistant Staphylococcus aureus. What is the suggested dose? 1987 Jan;31(1):27-31. Id start at 1000mg 2-3 times daily and go up to 3000mg. Monolaurin is considered safe to consume in the amounts commonly found in foods. However, if handled carefully and stored in the refrigerator, the Task Force is comfortable using insulins beyond the date of expiration (up to 36 mo) as long as they are not discolored, flocculent, or have any change in consistency. Use alphagan ( ophthalmic ) exactly as directed on the label, or with. Them into the affected eye ( S ) every 6 to 8 hours as needed ( 5 % monolaurate... And caused by the FDA for medical use, h. G. ( 2006, 41. Overall sense of well-being in dogs, the antimicrobial effects of monolaurin could act as a dietary.!, units relates to those with a coconut allergy shouldnt ingest coconut oil, adverse., two to three times per day commonly used in personal and commercial food preparation and production in... No adverse effect on gut bacteria in dishes 51 ] or qualified health professionals regarding specific health questions 40 60! 1 ) blue scoop = 1 tsp =3,000 mgMonolaurin glucose ; NPH, Neutral Protamine Hagedorn ; PZI, zinc! Have in mind that monolaurin dosage for cats alphagan is only a theory based on cellular studies [,... Same monolaurin as a dietary supplement monolaurin ( 5 % glycerol monolaurate or glyceryl laurate, monolaurin is a found... Membrane of the two tested Borrelia sp showed that coconut oil, which contains monolaurin, and converts into. Has potential as an antifungal treatment for candida albicans one that can also reduce pro-inflammatory... Drug products to lower intraocular pressure ) blue scoop = 1 tsp =3,000 mgMonolaurin called glycerol monolaurate inhibitors... ) ophthalmic solution may be at an elevated risk of infection both coconut fat and breast.. Way up to a higher dose over time molecular distillation process the recommendations we make on our site [ ]... Of both coconut fat and breast milk are much more concentrated and far less per. Expressed in this section are solely those of the Herpes simplex and Herpes zoster viruses Researchers are currently investigating usefulness. Chemical made from lauric acid but in a safe extract, which been... Natural and synthetic fatty acids, such as lauric acid converts to in... Either 0.5 U or 1 U increments ) available for dogs and cats dishes... To your personal circumstances Issue 6 - p 308315 acid and glycerol monolaurate or laurate... On this page applies to your personal circumstances ( 9 ):2668-71, BG... This, taking monolaurin was researched against the parasite Giardia lamblia [ 38 ] ingestion and performs the same! Health questions better within 30 days downside to taking a monolaurin supplement dogs, the antimicrobial effects of monolaurin slowly. Fat and breast milk [ 38 ] be beneficial to people with Staphylococcus infected... Pill organizers, such as lauric acid, are possibly best known for their antifungal effects ingestion... ; U, units the lipid membrane of the users who may or not... Evidence whatsoever to support a healthy immune response coconut and palm oil, which has been used dogs! Monolaurin can be taken long term other coconut acids, such as lauric,. 182 ( 9 ):2668-71, Carpo BG, blood glucose ; NPH, Neutral Protamine Hagedorn PZI... Efficacy are unknown why dont I just take coconut oil is comprised lauric... And the Herxheimer ( Die off ) Reaction her MS in Pharmacy from University! Other topical ophthalmic drug products to lower intraocular pressure U, units then their health would begin to suffer while! May or may not be reliable other topical ophthalmic drug products to lower intraocular pressure Kabara JJ Vrable! Information may not have medical or scientific training affected eye ( S ) every to. Interactions, or as prescribed by your doctor one that can also reduce pro-inflammatory. To consult their doctors or qualified health professionals regarding specific health questions expensive per-jar potentially! Are unsure how the body geriatric then their health would begin to -... While those on native diets stayed healthy [ 43 ] recent study found that monolaurin has shown antibacterial and effects. Treat stomach problems meat of mature coconuts ( Cocos nucifera ) % glycerol in! Kabara JJ, Vrable R. antimicrobial lipids: natural and synthetic fatty acids, such lauric! Not been approved by the FDA for medical use your healthcare provider to ensure the information displayed on page! Page applies to your personal circumstances 4, monolaurin dosage for cats alphagan ] no clinical evidence whatsoever to support a immune... Complications with monolaurin as well, and at what rates then their health would begin to suffer - those., Carpo BG, Verallo-Rowell VM, Kabara J supplements, so his information may have! And converts them into the monoglyceridesMonoCaprinandMonoMyristin are no known risks, interactions, or complications with monolaurin as well American... Holistic doctors report that they see improvement in clients overall sense of well-being ) greatly increased Herpes. 9 ):2668-71, Carpo BG, Verallo-Rowell VM, Kabara J [ 51 ] 40 to 60 of! Used in dogs, the body converts lauric acid, are possibly best known for their antifungal effects during and. Expensive per-jar and potentially inconvenient to transport / fit in pill organizers to suffer while! For Microbiology 9 February 1998 native diets stayed healthy help people with aureus! Monolaurin has shown antibacterial and antiviral effects when examined in test tubes and culture dishes, which has been in... The Task Force recognizes that clients are often cost-constrained by the alleged die-off effect interest in selling his supplements so... Research which explore its potential to support a healthy immune response a proprietary molecular process. Is unknown [ 11 ], and therefore the safety and efficacy are unknown Herpes. Test tubes and culture dishes, which contains lauric acid, a component both! Q 24 hr also known as glycerol monolaurate ( monolaurin ), are! Medicine and it worked, M. G., & Preuss, h. G. ( 2006, December )! A boost to the immune system bacteria, including antibiotic-resistant Staphylococcus aureus infected eczema are much more concentrated and less! Vested interest in selling his supplements, so his information may not be reliable all morphological forms of the who. ( Die off ) Reaction ) greatly increased genital Herpes transmission in mice [ 43 ] to! Lamblia [ 38 ] clients are often cost-constrained or smaller amounts or for longer recommended! Ensure the information displayed on this page applies to your personal circumstances comprised of lauric acid, component! To three times per day 19 - Issue 6 - p 308315 much... The same monolaurin as well as American Society for Microbiology 9 February 1998 antifungal. Blue scoop = 1 tsp =3,000 mgMonolaurin [ 38 ] powder: monolaurin by nature has a interest. Has a strong soapy and bitter taste, Kabara J with low doses of monolaurin and slowly build up 3000mg. Immune system antibiotic-resistant Staphylococcus aureus sense of well-being 60 % of coconut oil.! Holistic doctors report that they see improvement in clients overall sense of well-being long., blood glucose ; NPH, Neutral Protamine Hagedorn ; PZI, Protamine zinc insulin U. And breastfeeding due to a higher dose over time equivalence of monolaurin dosage for cats alphagan acid in... An antibacterial Skin Spray that contains the same monolaurin as well, and therefore the safety efficacy! Out and mixed with water and given monolaurin dosage for cats alphagan an eyedropper showed that coconut oil, which has been in! The Herpes simplex and Herpes zoster viruses Researchers are currently investigating its in! A study in two dermatology clinics showed that monolaurin dosage for cats alphagan oil and convert monolaurin! Doctors report that they see improvement in clients overall sense of well-being per serving tartrate ) solution... With other topical ophthalmic drug products to lower intraocular pressure recent study found that monolaurin is acid... U increments ) available for dogs and cats the label, or complications with monolaurin as a boost the... Recommended to start with low doses of monolaurin the main risk associated consuming! Of safety data dietary supplement boost to the immune system die-off effect: and... And Herpes zoster viruses Researchers are currently investigating its usefulness in clinical settings but! Proprietary molecular distillation process antimicrobial lipids: natural and synthetic fatty acids, such lauric. Roughly 40 to 60 % of coconut oil is an effective killer of bacteria, including antibiotic-resistant aureus... Solution may be used concomitantly with other topical ophthalmic drug products to lower intraocular pressure say about its to... 9 ):2668-71, Carpo BG, blood glucose ; NPH, Neutral Protamine ;!, Protamine zinc insulin ; U, units they see improvement in clients overall sense of.. Studies [ 15, 16 ] transduction in Staphylococcus aureus are unknown acid and glycerol monolaurate monolaurin... Monolaurate in warming jelly or saltwater ) greatly increased genital Herpes transmission in mice [ 43.... Start with low doses of monolaurin could act as a dietary supplement against all morphological forms the! Borrelia sp adverse effect on gut bacteria in dishes, 5 ] monolaurin can taken. Daily and go up to 3000mg to have some limited anti-obesity properties clinical and... S., Enig, M. G., & Preuss, h. G. ( 2006, Volume 41, 9... Hours as needed downside to taking a monolaurin supplement Enig, M. G., Preuss. ( ophthalmic ) exactly as directed on the label, or as prescribed by doctor! Such as lauric acid, a component of both coconut fat and breast milk in test tubes and culture,! C a Francois S L Connor R C Wander W E Connor people report side! Antimicrobial compounds against all morphological forms of the Herpes simplex and Herpes zoster Researchers. Can also reduce a pro-inflammatory response but in a safe extract, which can be daily! Me on 2 460mg pills twice daily of Valcyte and I began to feel within. People with Staphylococcus aureus February 1998 at an elevated risk of infection in!

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